*FUS Rabat 1-1 CS Sfaxien
| 22.09.2017 | CS Sfaxien | 1-0/p.4-5 | FUS Rabat | |
| 16.09.2017 | FUS Rabat | 1-0 | CS Sfaxien | |
MC Alger 1-2 Club Africain Tunis *
| 24.09.2017 | Club Africain Tunis | 2-0 | MC Alger | |
| 16.09.2017 | MC Alger | 1-0 | Club Africain Tunis | |
Hilal Ubayyid 1-7 TP Mazembe *
| 24.09.2017 | TP Mazembe | 5-0 | Hilal Ubayyid | |
| 16.09.2017 | Hilal Ubayyid | 1-2 | TP Mazembe | |
*SuperSport United 2-2 ZESCO United
| 23.09.2017 | ZESCO United | 2-2 | SuperSport United | |
| 15.09.2017 | SuperSport United | 0-0 | ZESCO United | |