*Rosenborg Youth 3-1 AIK Youth
| 19.10.2016 | AIK Youth | 1-3 | Rosenborg Youth | |
| 28.09.2016 | Rosenborg Youth | 0-0 | AIK Youth | |
Anderlecht Youth 1-3 Midtjylland Youth *
| 19.10.2016 | Midtjylland Youth | 3-1 | Anderlecht Youth | |
| 27.09.2016 | Anderlecht Youth | 0-0 | Midtjylland Youth | |
APOEL FC Youth 1-9 AS Roma Youth *
| 19.10.2016 | AS Roma Youth | 6-1 | APOEL FC Youth | |
| 28.09.2016 | APOEL FC Youth | 0-3 | AS Roma Youth | |
Breidablik Youth 0-7 AFC Ajax Youth *
| 19.10.2016 | AFC Ajax Youth | 4-0 | Breidablik Youth | |
| 28.09.2016 | Breidablik Youth | 0-3 | AFC Ajax Youth | |
HJK Helsinki Youth 0-1 Cork City Youth *
| 19.10.2016 | Cork City Youth | 1-0 | HJK Helsinki Youth | |
| 28.09.2016 | HJK Helsinki Youth | 0-0 | Cork City Youth | |
Domžale Youth 2-5 Cukaricki B. Youth *
| 19.10.2016 | Cukaricki B. Youth | 4-1 | Domžale Youth | |
| 28.09.2016 | Domžale Youth | 1-1 | Cukaricki B. Youth | |
FC Nitra Youth 2-8 Malaga Youth *
| 19.10.2016 | Malaga Youth | 5-0 | FC Nitra Youth | |
| 28.09.2016 | FC Nitra Youth | 2-3 | Malaga Youth | |
*Sparta Praha Youth 9-0 FK Mladost Youth
| 19.10.2016 | FK Mladost Youth | 0-5 | Sparta Praha Youth | |
| 28.09.2016 | Sparta Praha Youth | 4-0 | FK Mladost Youth | |
Gabala FC Youth 0-7 Dynamo M. Youth *
| 19.10.2016 | Dynamo M. Youth | 5-0 | Gabala FC Youth | |
| 21.09.2016 | Gabala FC Youth | 0-2 | Dynamo M. Youth | |
Dinamo Tb. Youth 1-8 Kairat Almaty Akademiya *
| 19.10.2016 | Kairat Almaty Akademiya | 5-1 | Dinamo Tb. Youth | |
| 29.09.2016 | Dinamo Tb. Youth | 0-3 | Kairat Almaty Akademiya | |
*Altınordu SK Youth 6-1 Levski Sofia U19
| 19.10.2016 | Levski Sofia U19 | 1-1 | Altınordu SK Youth | |
| 28.09.2016 | Altınordu SK Youth | 5-0 | Levski Sofia U19 | |
Puskás Akadémia U19 1-1 PAOK Youth *
| 19.10.2016 | PAOK Youth | 0-0 | Puskás Akadémia U19 | |
| 28.09.2016 | Puskás Akadémia U19 | 1-1 | PAOK Youth | |
*Maccabi Haifa Youth 8-2 Shakhter Solig. Youth
| 19.10.2016 | Shakhter Solig. Youth | 2-3 | Maccabi Haifa Youth | |
| 05.10.2016 | Maccabi Haifa Youth | 5-0 | Shakhter Solig. Youth | |
*Viitorul C. Youth 5-1 Sheriff Tiraspol Youth
| 19.10.2016 | Sheriff Tiraspol Youth | 0-1 | Viitorul C. Youth | |
| 28.09.2016 | Viitorul C. Youth | 4-1 | Sheriff Tiraspol Youth | |
*RB Salzburg Youth 8-0 Vardar Skopje Youth
| 19.10.2016 | Vardar Skopje Youth | 0-3 | RB Salzburg Youth | |
| 27.09.2016 | RB Salzburg Youth | 5-0 | Vardar Skopje Youth | |
Zrinjski Mostar Youth 0-9 FC Zürich Youth *
| 19.10.2016 | FC Zürich Youth | 6-0 | Zrinjski Mostar Youth | |
| 28.09.2016 | Zrinjski Mostar Youth | 0-3 | FC Zürich Youth | |