*BATE Borisov 2-1 Torpedo Zhodino
| 13.03.2022 | Torpedo Zhodino | 0-1 | BATE Borisov | |
| 09.03.2022 | BATE Borisov | 1-1 | Torpedo Zhodino | |
Dinamo Minsk 2-4 FC Gomel *
| 12.03.2022 | FC Gomel | 3-1 | Dinamo Minsk | |
| 06.03.2022 | Dinamo Minsk | 1-1 | FC Gomel | |
*FK Vitebsk 2-1 Dinamo Brest
| 12.03.2022 | Dinamo Brest | 1-0 | FK Vitebsk | |
| 06.03.2022 | FK Vitebsk | 2-0 | Dinamo Brest | |
*Neman Grodno 3-0 Dnepr Mogilev
| 13.03.2022 | Dnepr Mogilev | 0-0 | Neman Grodno | |
| 07.03.2022 | Neman Grodno | 3-0 | Dnepr Mogilev | |