Fast Clube/AM 0-4 Novorizontino/SP *
| 10.01.2021 | Novorizontino/SP | 3-0 | Fast Clube/AM | |
| 03.01.2021 | Fast Clube/AM | 0-1 | Novorizontino/SP | |
*Floresta/CE 3-1 América/RN
| 10.01.2021 | América/RN | 1-1 | Floresta/CE | |
| 02.01.2021 | Floresta/CE | 2-0 | América/RN | |
Marcilio Dias/SC 2-6 Altos/PI *
| 10.01.2021 | Altos/PI | 5-1 | Marcilio Dias/SC | |
| 03.01.2021 | Marcilio Dias/SC | 1-1 | Altos/PI | |
*Mirassol/SP 5-3 Aparecidense/GO
| 09.01.2021 | Aparecidense/GO | 2-3 | Mirassol/SP | |
| 02.01.2021 | Mirassol/SP | 2-1 | Aparecidense/GO | |