68 Aksaray Bld. 4-5 Iğdır FK *
| 18.05.2022 | Iğdır FK | 3-2 | 68 Aksaray Bld. | |
| 13.05.2022 | 68 Aksaray Bld. | 2-2 | Iğdır FK | |
*Arnavutköy Bld. 4-1 Bursa Yıldırımspor
| 17.05.2022 | Bursa Yıldırımspor | 0-1 | Arnavutköy Bld. | |
| 12.05.2022 | Arnavutköy Bld. | 3-1 | Bursa Yıldırımspor | |
52 Orduspor 2-3 Iskenderunspor *
| 18.05.2022 | Iskenderunspor | 2-1 | 52 Orduspor | |
| 13.05.2022 | 52 Orduspor | 1-1 | Iskenderunspor | |
*Artvin Hopaspor 2-1 Kutahyaspor
| 17.05.2022 | Kutahyaspor | 0-0 | Artvin Hopaspor | |
| 12.05.2022 | Artvin Hopaspor | 2-1 | Kutahyaspor | |
Ofspor 3-4 Fethiyespor *
| 17.05.2022 | Fethiyespor | 3-2 | Ofspor | |
| 12.05.2022 | Ofspor | 1-1 | Fethiyespor | |
Orduspor 1-3 İçel İdman Yurdu *
| 17.05.2022 | İçel İdman Yurdu | 3-0 | Orduspor | |
| 12.05.2022 | Orduspor | 1-0 | İçel İdman Yurdu | |