Brøndby IF 3-5 AFC Ajax *
| 24.08.2005 | AFC Ajax | 3-1 | Brøndby IF | |
| 10.08.2005 | Brøndby IF | 2-2 | AFC Ajax | |
Anorthosis FC 1-4 Rangers FC *
| 24.08.2005 | Rangers FC | 2-0 | Anorthosis FC | |
| 09.08.2005 | Anorthosis FC | 1-2 | Rangers FC | |
Valerenga 1-1 Club Brugge *
| 24.08.2005 | Club Brugge | 1-0/p.4-3 | Valerenga | |
| 09.08.2005 | Valerenga | 1-0 | Club Brugge | |
*FC Artmedia Bratislava 0-0 FK Partizan
| 23.08.2005 | FK Partizan | 0-0/p.3-4 | FC Artmedia Bratislava | |
| 10.08.2005 | FC Artmedia Bratislava | 0-0 | FK Partizan | |
CSKA Sofia 2-3 Liverpool *
| 23.08.2005 | Liverpool | 0-1 | CSKA Sofia | |
| 10.08.2005 | CSKA Sofia | 1-3 | Liverpool | |
*Manchester United 6-0 Debrecen VSC
| 24.08.2005 | Debrecen VSC | 0-3 | Manchester United | |
| 09.08.2005 | Manchester United | 3-0 | Debrecen VSC | |
Wisła Kraków 4-5 Panathinaikos *
| 23.08.2005 | Panathinaikos | 4-1 AET | Wisła Kraków | |
| 09.08.2005 | Wisła Kraków | 3-1 | Panathinaikos | |
*Rapid Wien 2-1 Lokomotiv Moscow
| 23.08.2005 | Lokomotiv Moscow | 0-1 | Rapid Wien | |
| 10.08.2005 | Rapid Wien | 1-1 | Lokomotiv Moscow | |
*Real Betis 3-2 AS Monaco
| 23.08.2005 | AS Monaco | 2-2 | Real Betis | |
| 09.08.2005 | Real Betis | 1-0 | AS Monaco | |
Shakhtar Donetsk 1-3 Inter Milan *
| 24.08.2005 | Inter Milan | 1-1 | Shakhtar Donetsk | |
| 10.08.2005 | Shakhtar Donetsk | 0-2 | Inter Milan | |
*Anderlecht 4-1 Slavia Praha
| 24.08.2005 | Slavia Praha | 0-2 | Anderlecht | |
| 10.08.2005 | Anderlecht | 2-1 | Slavia Praha | |
Sporting Lisboa 2-4 Udinese Calcio *
| 23.08.2005 | Udinese Calcio | 3-2 | Sporting Lisboa | |
| 10.08.2005 | Sporting Lisboa | 0-1 | Udinese Calcio | |
Steaua Bucuresti 3-4 Rosenborg BK *
| 23.08.2005 | Rosenborg BK | 3-2 | Steaua Bucuresti | |
| 10.08.2005 | Steaua Bucuresti | 1-1 | Rosenborg BK | |
Everton 2-4 Villarreal CF *
| 24.08.2005 | Villarreal CF | 2-1 | Everton | |
| 09.08.2005 | Everton | 1-2 | Villarreal CF | |
FC Basel 2-4 Werder Bremen *
| 24.08.2005 | Werder Bremen | 3-0 | FC Basel | |
| 10.08.2005 | FC Basel | 2-1 | Werder Bremen | |